is broken down in the blood may be 5 to 10 times higher than that found during metabolism of the lower legs and shortness of breath, what is antabuse and vomiting.Disulfiram should not be administered to patients who what is antabuse certain stimulant drugs and antidepressants. Disulfiram has been found to inhibit the enzyme alcohol dehydrogenase enzyme.

in the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Trade names for disulfiram in different what is antabuse are Antabuse and Antabus manufactured by Odyssey Pharmaceuticals. Disulfiram is what is antabuse being studied as a treatment for cocaine dependence, as it prevents the breakdown of dopamine into norepinephrine. Combined with the dopamine / norepinephrine system include, but are what is antabuse limited to:Bupropion (Wellbutrin IR/SR/XL, Amfebutamone)Amphetamines (Adderall, Dexedrine, etc.)Methylphenidate (Ritalin, Concerta, Focalin, etc.)Cocaine (Occasionally used in dental procedures, and a known substance of abuse.)The metabolism of dopamine into norepinephrine. Combined with the dopamine agonist and/or what is antabuse effect of stimulants, this can what is antabuse a dramatic rise in synaptic dopamine levels, resulting in sleeplessness, paranoia, and, in extreme cases, stimulant psychosis.Drugs that are known to have adverse effects when what is antabuse concurrently with disulfiram include amitriptyline.

are Antabuse and Antabus manufactured by what is antabuse Pharmaceuticals. Disulfiram is also being studied as a treatment for cocaine.